Agau, a 6-foot-8 forward from Omaha, NE, is leaving mainly to find more playing time. Agau, originially from Sudan, has 11 minutes on the floor in just three games this season. He has one rebound and missed his only shot of the season.
Agau spent part of this summer recovering from a sports hernia surgery he underwent in late July. He was sidelined for more than two months prior to the start of practices for this season.
"I sat down with Akoy and we agreed that it is in the best interest for his future to transfer to another university where playing time will be more readily available," Pitino said.
"I'm very fond of Akoy as a person...We wish him nothing but good fortune going forward and will always consider him a part of this program."
Last year as a freshman, Agau appeared in 19 games for the Cardinals, averaging 1.1 rebounds and 0.9 points in 5 minutes per game. His playing time was limited in part by the growing presence of Mangok Mathiang, Chinanu Onauaku and Anas Mahmoud in Louisville's frontcourt rotation.
Louisville, 9-0 so far this season, plays next against Western Kentucky on Saturday afternoon.