Upsets are the hallmark of the NCAA tournament. Notre Dame managed to survive against Northeastern in the first game of this year's round of 64, but 14th-seeded UAB knocked off 3rd-seeded Iowa State on Thursday.
Keep track of all the tournament's upsets here.
No. 14 UAB vs. No. 3 Iowa State
The Blazers beat the Cyclones, 60-59, for their first NCAA tournament win since 2005. Robert Brown, a redshirt junior transfer from Virginia Tech, led all scorers with 21 points. UAB frustrated Iowa State star Georges Niang, limiting him to just 11 points on 4-15 shooting.
No. 14 Georgia State vs. No. 3 Baylor
This is only the second time ever that two No. 14 seeds have won their opening games. The last time was in 1995 when Old Dominion defeated Villanova in triple overtime and Weber State beat Michigan state.
Junior guard R.J. Hunter hit the game-winning three-pointer with under three seconds to play. His coach, and father, Ron, was so excited he fell out of his chair.
No. 11 UCLA vs. No. 6 SMU
Down 59-58 and with time expiring, UCLA guard Bryce Alford, the son of UCLA coach Steve Alford, launched a shot to win the game that bounced off the front rim. SMU's Yannick Moriera, however, was called for goal-tending on the play, putting UCLA up 60-59. SMU would miss two final shot attempts, and the Bruins would win the game.
No. 10 Ohio State vs. No. 7 VCU
Despite facing a double-digit deficit in the first half, Ohio State rallied before halftime to close the gap to just one point. After a back-and-forth second half ended in a stalemate, the Buckeyes claimed a 75-72 victory in overtime. Ohio State guard D'Angelo Russell led the team with 28 points. He also had six rebounds and two blocks.
No. 8 North Carolina State vs. No. 1 Villanova
The Wildcats were the first No. 1 seed to fall this year, losing 71-68 to N.C. State. Villanova's Darrun Hilliard led all scorers with 27 but he and JayVaughn Pinkston were the only Wildcats to score in double figures. Four of the Wolfpack's starters notched double-digit points. Lennard Freeman and Abdul-Malik Abu both recorded double-doubles.
No. 7 Michigan State vs. No. 2 Virginia
Senior point guard Travis Trice led the Spartans to a 60-54 victory. Virginia and Villanova, the top two seeds in the East region, were both eliminated before the end of the tournament's first weekend. This is this first time since 2004 that the top two seeds in a region have failed to advance to the Sweet 16.
No. 7 Wichita State vs. No. 2 Kansas
The Shockers prevailed in the team's first meeting since 1993, 78-65. Junior point guard Fred VanVleet had 17 points, six rebounds and six assists. The Shockers shot 50% on three-pointers, while the Jayhawks were 28.6% from behind the arc. After being eliminated in the Round of 32 last season, the Shockers are headed back to the Sweet 16 for the second time in three years. They advanced to the Final Four in 2013.