The apparent injury occurred on a running play in which Watson was not tackled. The true freshman was helped off the field and went to the locker room.
Watson had not played since he broke a bone in his throwing hand in an Oct. 11 win over Louisville. Shortly after Cole Stoudt replaced Watson in the game, the senior threw a pick-six that gave the Yellow Jackets a 6-3 lead.
Watson has thrown for 1,176 yards with 12 touchdowns and two interceptions this season. He was rated the No. 1 dual-threat quarterback in the class of 2014 by Rivals.com.
Clemson is 7-2 (6-1 ACC) and ranked 19th in the latest edition of the College Football Playoff rankings.