In 11 games this season, Williams has rushed for 609 yards and 10 touchdowns.
Florida State (12-0) was ranked fourth in the latest edition of the College Football Playoff rankings.
If they beat the No. 11 Yellow Jackets (10-2) on Saturday, the Seminoles are expected to remain in the top four, meaning they would have a spot in one of the two Playoff semifinals.
The Playoff selection committee will announce the four teams selected to the Playoff on Sunday.