David Freese was replaced by Daniel Descalso in the fifth inning on Monday night.
Stephen Dunn/Getty Images

LOS ANGELES (AP) -- St. Louis third baseman David Freese left Game 3 of the NL championship series in the fifth inning Monday night with tightness in his right calf.

Pinch-runner Daniel Descalso then made a major mistake in his place, getting doubled off second base to hurt a St. Louis rally.

Freese singled to lead off the fifth with the Cardinals' first hit off Los Angeles Dodgers left-hander Hyun-Jin Ryu, but the Cardinals' training staff came out to meet him at first base.

After Freese advanced to second on Matt Adams' single, Descalso emerged from the St. Louis dugout to replace Freese.

Descalso then took off for third base on Jon Jay's tailing fly to shallow left field, and Carl Crawford doubled him up.

The Cardinals failed to score in the inning and trailed 2-0.

Freese was the MVP of the 2011 NLCS and the World Series, setting a major league record with 21 postseason RBIs.

After going 1 for 2 in Game 3, he is batting .192 in the postseason, going 5 for 26 with one homer and four RBIs.

SI Apps
We've Got Apps Too
Get expert analysis, unrivaled access, and the award-winning storytelling only SI can provide - from Peter King, Tom Verducci, Lee Jenkins, Seth Davis, and more - delivered straight to you, along with up-to-the-minute news and live scores.