With around five minutes remaining in the second quarter, LeBron James dribbled to his right near the three-point line before threading a one-handed bounce pass between two defenders. Positioned close to the basket, Marion caught the ball, set his feet and exploded for a one-handed dunk despite Sanders' block attempt.
Entering Tuesday, Sanders was tied for 10th in the NBA with 1.8 blocks per game.
Marion is in his 16th season in the league. The 36-year-old signed a one-year deal with the Cavaliers this summer after spending his previous five seasons with the Mavericks. Over 15 games this season, Marion has averaged 5.8 points, 3.8 rebounds and 1.3 assists.
The Cavaliers (8-7) have won three consecutive games.