The Colts host the Eagles on Monday Night Football in Week 2. Indianapolis is 0-1 after narrowly falling to the Denver Broncos in Week 1, while Philadelphia is 1-0 after coming back to defeat the Jacksonville Jaguars.
You can follow the game with live stats and play-by-play here.
Details for Monday's game are below:
Kickoff: 8:30 p.m. ET
Live stream: The game can be live streamed here.
TV coverage: ESPN
Odds: The Colts are three-point favorites, according to Bovada, as of Monday morning.
The Colts have won four of the last five meetings with the Eagles, which includes a 45-21 win the last time they played in Indianapolis in 2006.
Defensive end Robert Mathis tore his Achilles tendon last week and is out for the season.
Starting linebacker Jerrell Freeman is out for Monday's game due to a hamstring injury.
Defensive lineman Art Jones will be a game-time decision due to a shoulder injury.
The Colts have started 0-2 in a season just one time since 1998.
Quarterback Andrew Luck had 53 attempts in Week 1, the third most he's had in his career and more than he had in any game last season.
In his last two games against Philadelphia, wide receiver Hakeem Nicks has 16 catches for 193 yards.
The Colts haven't lost back-to-back games since head coach Chuck Pagano took over in 2012.
Colts safety Colt Anderson played for the Eagles from 2010-13.
Running back Trent Richardson had six carries for 20 yards in Week 1, an average of 3.3 yards per carry. He averaged 3.0 yards per carry in 2013.
Philadelphia defeated the Colts in the teams' last meeting, winning 26-24 in 2010.
The Eagles are without starting offensive tackle Allen Barbre and offensive guard Evan Mathis in Week 2 after both were injured in Week 1. Barbre is out for the season, while Mathis is out at least eight weeks.
Last week, Philadelphia became the first team in NFL history to win a game by at least 17 points after being shut out and trailing by at least 17 points at halftime.
The Eagles have won eight of their last nine regular season games.
Philadelphia had six plays of 20-plus yards in the season opener after leading the NFL in that category in 2013.
Quarterback Nick Foles had one interception in 45 attempts in Week 1 after having just two in 317 attempts last season.
The Eagles have started 2-0 in just two seasons since 1993.
Wide receiver Jeremy Maclin had a 68-yard touchdown catch in Week 1, the third longest of his career.
Running back Darren Sproles had a 49-yard touchdown run in the season opener, the longest rush of his career.
Defensive end Fletcher Cox was fined $16,537 last week for a hit on Jaguars quarterback Chad Henne in Week 1.
- Ben Estes