The 27-year-old injured his hamstring in the third quarter of the Jets' 31-24 loss to the Green Bay Packers last Sunday. He returned for one play before leaving the game for good.
The receiver also dealt with the injury during training camp.
On Wednesday, head coach Rex Ryan said he was "confident" that Decker would play against the Bears.
In two games this season, Decker has caught nine passes for 137 yards and a touchdown.
- Sarah Barshop and Molly Geary