Jim Wyatt of the Tennessean reports that after leaving the game, Locker was seen with a "big wrap" on his right hand/thumb.
Locker completed 8-of-11 passes for 79 yards and a touchdown before leaving the game. He missed last week's matchup against the Colts with a right wrist/hand injury.
In four years with Tennessee, Locker has thrown for 4,659 yards and 25 touchdowns. He played only three games last season due to a Lisfranc injury to his right foot.
The Titans entered Sunday at 1-3 on the season.
-- Alex Suskind