Beason suffered the injury to his right foot during off-season practice, fracturing the sesamoid bone and tearing ligaments in June, and has been attempting to play through it since then.
He returned in the team's Week 1 game against the Detroit Lions, but aggravated the injury during New York's Week 2 match-up with the Arizona Cardinals. After missing four games, he returned against the Dallas Cowboys, but had to leave the game early.
Beason, 29, left Dallas and visited Dr. Robert Anderson in North Carolina, and the decision was made to end his season early.
Jameel McClain filled in for Beason on Sunday, and will likely take over Beason's defensive responsibilities going forward, Raanan writes.
Beason had been using specially-designed, double-carbon-fiber-plated cleats in order to play with the injury.
New York acquired Beason early last year; he re-signed with the team in March, agreeing to a three-year, $17 million contract.
The Giants are 3-4 and in third place in the NFC East. They host the Indianapolis Colts this coming Monday.
- Christopher Woody