Foster injured his groin in Houston's game Nov. 2 against the Philadelphia Eagles and was forced to leave in the third quarter. He didn't practice all this week and had been listed as questionable Friday before he was ruled out.
Foster currently leads the AFC and is second in the NFL in rushing with 822 yards on 161 carries this season.
Rookie Alfred Blue will start in Foster's place. Blue has 68 carries for 234 yards this season.
“I expect a heavier load every week," Blue said this week, according to the Texans' official website. "You just never know what might happen in the game. I prepare each week to be ready no matter what the situation is.”
Foster also missed the Texans' Week 3 game against the New York Giants due to a hamstring injury and missed eight games last season due to a back injury, for which he underwent surgery last November.
Houston is 4-5 this season and in second place in the AFC South. The team had a bye last week.
- Ben Estes