Ellington was injured during Sunday's loss to the Atlanta Falcons and left the game in the second quarter. In his weekly appearance on SiriusXM NFL's Late Hits, Arians said that the running back likely would not practice.
So far this year, Ellington has dealt with several injuries, including a foot injury that has lingered all season. In 12 games, he has 660 rushing yards with three touchdowns. He is the only Cardinal to rush for more than 100 yards on the season.
The Cardinals also lost two other starters in the first half of Sunday's game. Safety Tyrann Mathieu fractured his left thumb and is expected to miss three weeks. Guard Paul Fanaika sprained his left ankle in the second quarter.
Arizona is in first in the NFC West with a 9-3 record. The Cardinals are one game ahead of the Seattle Seahawks and two games ahead of the San Francisco 49ers. They host the Kansas City Chiefs (7-5) on Sunday.
- Danielle Zhu