“Obviously that's a devastating loss to us and to him,” head coach Rex Ryan told reporters on Sunday.
A former sixth round pick by the Green Bay Packers, Wynn recorded 17 tackles and two sacks last season.
Last week, the Bills claimed defensive end IK Enemkpali on waivers after he was released by the New York Jets for punching Geno Smith in the face. Enemkpali was given second-team reps during Buffalo's 25–24 preseason loss to the Carolina Panthers on Friday.
The Bills kick off the 2015 season on Sept. 13 at home against the Indianapolis Colts.
- Molly Geary