The Indianapolis Colts (2–3) can move into a tie for first place in the AFC South when they visit the Houston Texans (3–2) as three-point road underdogs at sportsbooks monitored by OddsShark.com in the Week 6 Sunday night game.
The Colts are coming off a 29–23 win over the Chicago Bears as 3.5-point home favorites last week while the Texans lost to the Minnesota Vikings 31–13 as six-point road underdogs.
Indianapolis has won six of the past seven meetings in the divisional rivalry, going 5-1-1 against the spread, according to the OddsShark NFL Database. However, this will be the first time Houston quarterback Brock Osweiler will square off with Indianapolis’s Andrew Luck after signing a four-year, $72 million contract with the Texans in the offseason.
Osweiler has experienced an up-and-down first season in Houston, playing well in the team’s three wins and poorly in the two losses, throwing for fewer than 200 yards both times. Luck has alternated throwing for more than 300 yards in each game, including 322 against Chicago. The Colts have won the last two times he has topped 300 yards.
Before that key matchup kicks off, there are three earlier games featuring intriguing storylines.
First, the Kansas City Chiefs (2–2) will visit the Oakland Raiders (4–1) in a pick’em affair according to oddsmakers. The Chiefs have won 10 of the past 13 road meetings with the Raiders both straight up and against the spread in the AFC West rivalry. Oakland has also failed to cover six straight at home.
In the NFC, the Green Bay Packers (3–1) host the Dallas Cowboys (4–1), who have won four in a row since losing their season opener to the New York Giants.
The Packers are listed as four-point home favorites and have won the past five meetings while going 4–1 ATS. However, this is the first time Green Bay will be facing quarterback Dak Prescott and running back Ezekiel Elliott, who are two favorites to win Rookie of the Year honors.
The Atlanta Falcons (4–1) are also riding a four-game winning streak and visit the Seattle Seahawks (3–1) as 6.5-point road underdogs. The Falcons just upset the defending Super Bowl champion Denver Broncos 23–16 last week as 3.5-point road dogs and have won four of the past five meetings with the Seahawks.