Bortuzzo, who turns 26 later this month, has played in 38 games this season. He has missed time due to injury and illness and was also a healthy scratch on a number of occasions. He averaged 15:28 of ice time and had a minus-six rating.
Cole, 26, has played in 54 of the Blues' 63 games this season, averaging 15:03 on the ice. He has nine points and a plus-16 rating.
Both players will be restricted free agents after this season.
The Penguins are currently third in the Metropolitan Division and the Blues are second in the Central.
- Dan Gartland