Lundqvist, 33, had not played since early February while dealing with a sprained blood vessel in his neck.
The injury was diagnosed after he remained in that game and started New York's next game against the Florida Panthers.
During Lundqvist's 25-game absence, the Rangers went 18-7. The team clinched a playoff spot earlier this week.
Lundqvist, a three-time All-Star, has allowed an average of 2.25 goals per game and recorded a save percentage of 92.2 this season.
On Saturday, Lundqvist stopped 26 shots but allowed four goals as the Rangers fell, 4-2.
At 47-20-7, the Rangers sit in first place in the Metropolitan division.