Orozco sustained the injury while practicing a dismount off a high bar, according to USA Today.
Orozco's ACL injury is just the latest health setback for the 23-year-old. Orozco has torn his Achilles tendon twice, which caused him to skip last year’s World Championships.
In the 2012 London Summer Olympics, Orozco represented the U.S. in the men’s artistic team all-around, as well as the men’s individual all-around.
Following an impressive performance on the pommel horse in front of head coach Kevin Mazeika, Orozco was set to participate in the pommel horse in Rio, as well as the high bar and parallel bars.
Reigning Olympic bronze medalist Danell Leyva will fill Orozco’s spot.
The team will begin competition on Aug. 6.