Los Angeles Angels first baseman Albert Pujols left Wednesday's game against the Boston Red Sox after the top of the fourth inning with soreness in his right calf. He appeared to struggle while running the bases following a leadoff double. (He came around to score on a Mark Trumbo single.)
Peter Abraham of the Boston Globe has details on how the Angels adjusted their lineup.
More info if it becomes available, but the prevailing sentiment is that Pujols' removal was a precautionary measure and that he will probably be considered as day-to-day.
After a slow start in his first season in Anaheim, Pujols is up to .283 with 28 home runs and 86 RBIs.
UPDATE: More details from Mike DiGiovanna of the Los Angeles Times: