Maria Sharapova withdrew from the U.S. Open Wednesday because of bursitis in her right shoulder, tournament organizers announced.
Sharapova won the tournament in 2006 and was the third seed for the Open, which starts Monday.
"Maria has informed us that she will be unable to compete at the U.S. Open this year due to a right shoulder bursitis and has withdrawn from the tournament," according to a statement from U.S. Open tournament director David Brewer. "We wish her a speedy recovery and look forward to her return to New York next year."
Agnieszka Radwanska will move up to the No. 3 seed in women's singles and Anastasia Pavlyuchenkova becomes the No. 32 seed. Serena Williams is the tournament's top seed and defending champion. Victoria Azarenka is seeded second. Sharapova has played in only one match on tour since her second-round loss in June at Wimbledon.