New England placed Vereen on the Injured Reserve-Designated to Return list. He can't be activated for at least eight weeks. Because the Patriots have a Week 10 bye, the earliest he could be back is Week 11.
Vereen rushed for 101 yards and caught seven passes against the Bills on Sunday. After starter Stevan Ridley was benched for fumbling, Vereen became New England's featured back.
But any hopes that he would continue to cut into Ridley's carries ended when news of the wrist injury emerged. Vereen had surgery, and early reports speculated that he would only be out for a "few weeks." But those reports were overly optimistic.
BURKE: Reggie Bush, Jay Cutler benefit greatly from new wrinkles The Patriots already are dealing with injures to key members of their offense. Tight end Rob Gronkowski missed Week 1 and reportedly won't be ready for Thursday night's game with the Jets. Receiver Danny Amendola, one of the team's bright spots against Buffalo, also may miss Thursday's game.