The Houston Texans will be without their All-Pro left tackle when they take on the defending champions on Sunday.
2012 first-team All-Pro member Duane Brown did not travel with the team to Baltimore on Saturday morning and has been ruled out for the game against the Ravens with a sprained toe, the Texans announced.
Brown's 78-game consecutive starts streak will be snapped. Sixth-year pro Ryan Harris, in his second year with Houston, will start in his place.
Brown, a 28-year-old former first round pick in the first year of a six-year, $53.4 contract extension, was listed as questionable and did not practice after suffering the injury during last week's overtime win over the Tennessee Titans.
He is the third Pro Bowl tackle to go down this week, as the Denver Broncos lost Ryan Clady for the season and the Seahawks placed Russell Okung on the IR-to-return list, both also with foot-related injuries.