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San Francisco 49ers vs. Indianapolis Colts NFL Week 7 Odds, Plays and Insights

The San Francisco 49ers (2-3) are favored by 4 points as they look to halt a three-game slide in a matchup with the Indianapolis Colts (2-4) on Sunday, October 24, 2021 at Levi's Stadium. The point total is set at 44.

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Odds for 49ers vs. Colts

Over/under insights

  • San Francisco and its opponents have gone over the current 44-point total in three of five games this season.
  • Indianapolis' games have gone over 44 points in four of six chances this season.
  • The two teams combine to score 46.6 points per game, 2.6 more than the total in this contest.
  • This contest's over/under is 1.6 points under the 45.6 these two squads combine to give up per game in 2020.
  • 49ers games this season feature an average total of 49.2 points, a number 5.2 points higher than Sunday's over/under.
  • The 46.1 PPG average total in Colts games this season is 2.1 points more than this game's over/under.
  • Thus far this year San Francisco has one win against the spread.
  • The 49ers have yet to cover the spread this season when favored by 4 points or more.
  • San Francisco's games this year have gone over the total in two out of five opportunities (40%).
  • The 49ers rack up 23.4 points per game, comparable to the 21.8 per contest the Colts allow.
  • When San Francisco scores more than 21.8 points, it is 0-2 against the spread and 1-1 overall.
  • The 49ers average only 1.7 more yards per game (368.2), than the Colts allow per matchup (366.5).
  • San Francisco is 0-2 against the spread and 1-1 overall when the team piles up more than 366.5 yards.
  • The 49ers have turned the ball over seven times this season, five fewer than the Colts have forced (12).
  • Click over to SISportsbook and find the latest spread, moneyline and total for San Francisco's matchup with the Colts.
  • Indianapolis has four wins against the spread in six games this season.
  • The Colts have covered the spread twice this season when underdogs by 4 points or more (in three chances).
  • Indianapolis has eclipsed the over/under in 50% of its opportunities this season (three times in six games with a set point total).
  • The Colts average just 0.6 fewer points per game (23.2) than the 49ers surrender (23.8).
  • Indianapolis is 4-0 against the spread and 2-2 overall in games when it puts up more than 23.8 points.
  • The Colts average 37.7 more yards per game (367.5) than the 49ers give up (329.8).
  • Indianapolis is 4-1 against the spread and 2-3 overall when the team picks up more than 329.8 yards.
  • The Colts have turned the ball over three more times (5 total) than the 49ers have forced a turnover (2) this season.

Home and road insights

  • 49ers home games this season average 51.3 total points, 7.3 more than this outing's over/under (44).
  • Indianapolis is 1-2 overall, with two wins against the spread, away from home.
  • This year, in three road games, Indianapolis has gone over the total twice.
  • The average point total in Colts away games this season is 45.0 points, 1.0 more than this matchup's over/under (44).

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