Colter made 7 of 8 3-point attempts - also a career high for the junior - one short of the school record.
Duquesne hit 35 of 64 shots for 54.7 percent, shooting even better from 3-point range at 56 percent (14 of 25). The Dukes dominated the boards 48-30.
The Division II Big Blues led 8-4 before Duquesne went on a 20-4 run. The Dukes led 52-25 at halftime and were up by as many 41 in the second half.
Bluefield State was led by Dajon Reno, who scored 22 points, and Mark Durgan, who added 11.