Iba Camara made a free throw to give New Hampshire (1-1) a 20-point lead with four minutes to play in the first half, and they led by double digits the rest of the way. Daniel Dion hit a 3-pointer with 1:25 left before the break to give the Wildcats a 37-14 halftime lead.
New Hampshire opened the second half on a 22-2 run. Camara finished with nine points and grabbed 15 boards for the Wildcats, who outrebounded the Terriers 51-24.
Levi Barnes had 12 points on 6-of-13 shooting to lead Thomas College, which shot just 15 of 54 for 27.8 percent from the floor.
It was the first meeting between the schools.