Jacksonville State answered with a 10-0 run to pull within 53-42 with 6:00 to play, but the Gamecocks did not get any closer.
Keane was 5 of 10 from the field, including two 3-pointers. Grady finished on 4-of-11 shooting and was 4 of 4 from the line. Mason chipped in 10 points and grabbed eight rebounds for the Vikings (2-1), who outrebounded the Gamecocks 39-24.
The game was part of the Global Sports Showcase.