Astroth, who made 5 of 7 from the field, was the only player in double figures for Towson (2-1).
Towson jumped to a 13-4 lead midway through the first half as Central Connecticut (0-3) came out cold.
The Blue Devils, who trailed 26-15 at the break, warmed up in the second half cutting the lead to 40-37 following Faronte Drakeford's 3-pointer with 8:30 left. The Tigers answered quickly with an 8-0 run to lead 48-37 with 5:10 remaining. CCSU got no closer than seven after that.
Matt Mobley and Khalen Cumberland had 14 apiece for CCSU.