La Salle (4-0) shot 47 percent and was 4 of 11 on 3-pointers. Jerrell Wright scored 19 points and grabbed 9 rebounds as the Explorers limited St. Francis (0-4) to just 35 percent from the floor. Steve Zack added 14 points and 13 boards for La Salle.
St. Francis led through the first five minutes, but an 8-0 run - including a dunk by Wright - opened things up for La Salle. The Explorers closed the half on an 11-2 run and led 34-23 at intermission.
The Terriers cut the deficit to four on a 4-point play by Tyreek Jewell with 10:15 left, but a 13-3 LaSalle run gave the Explorers a comfortable edge down the stretch.