Howard is now just 20 points away from making 1,000 points in his Detroit career.
Detroit (5-3) jumped out to a 29-15 lead midway through the first half, pushed that to 60-34 at the half and were rolling 88-48 with 10:42 left in the game.
The Titans nailed 12 of 22 3-point attempts and made 41 of 68 field goal attempts (60.3 percent) while limiting the Saints to 39.3 percent. Detroit also won the rebound battle, grabbing 41 compared to 24 for the Saints.
Jake Bullock led the Aquinas with eight points. The Saints were forced into 23 turnovers.