Oral Roberts (2-4) nursed a short lead for much of the second half, but a 7-0 run - Chris Golden's 3-pointer and a pair of free throws by both Kyndahl Hall and Richaud Gittens - drew Weber State to within one at 55-54 with 3:48 left.
The Golden Eagles scored the next seven points, including a layup by Korey Billbury and a jumper by Brandon Conley to go up 59-54 with 59 seconds left. But Senglin made a pair from the line and Gittens drilled a trey to make it a two-point game. Oral Roberts' Obi Emegano then missed a pair of free throws, setting up Senglin's game-winner.
Gittens led Weber State (3-3) with 16 points and Golden had 15 while Senglin finished with nine. Billbury paced Oral Roberts with 17 points.