Elijah Wilson scored 13 points and Colton Ray-St Cyr and Josh Cameron added 12 apiece for the Chanticleers (6-2). Marcus Freeman collected 13 rebounds for Coastal Carolina, which had a 41-rebound margin over the Owls (7-7). The Chanticleers outscored the Owls 44-6 in the paint.
Coastal Carolina's Warren Gillis went over 1,000 career points.
Ty Johnson led Warren Wilson with 13 points and Justin Gonyea added 11. The Owls made just 13 of 52 shots for 25 percent, including 9 of 33 attempts from the arc. They also had 19 turnovers, 13 coming on steals.
The Chanticleers led 41-21 at halftime
Warren Wilson is a member of the United States Collegiate Athletic Association.