With Bowen, a senior, reaching a career high, and White, a freshman, one short of matching his best, the Hoyas (6-3) got 42 points from their backups.
Georgetown hit 10 of 11 free throws in the first half and opened a 29-18 lead. Radford was 8 of 9 for the game.
In the second half the Hoyas shot 50 percent, including 6 of 13 on 3-pointers, to pull away.
Mikael Hopkins had seven rebounds as Georgetown dominated the boards 40-22. D'Vantes Smith-Rivera had six of the Hoyas' 19 assists to go with nine points, five rebounds and three steals.