Mitola, who was 4 of 9 from 3-point range, has scored in double figures in all nine games this season.
The Big Green had a comfortable 33-22 lead at the break and stretched that to 51-37. Mercer tried to charge back when Ike Nwamu hit two straight jumpers to pull to 51-41 with 7:19 left in the game. Crescenzi responded with a 3-pointer that started a 13-0 run for a 64-41 lead with 2:54 remaining.
Dartmouth made 10 of 19 3-point attempts (52.6 percent) to shoot 24 of 49 from the floor (49 percent).
Nwamu had 13 points and Jordan Strawberry added 11 for Mercer (5-5).