Dominique Dunning posted a double-double with 11 points and 10 rebounds for the Anteaters (7-6). Mike Best scored 10 points and Travis Souza had nine. The team hit 66.1 percent from the field and outrebounded Hampden-Sydney 39-19.
UC Irvine jumped to a 24-8 advantage early in the first period and led 35-18 at the break.
Furious back-and-forth action in the first four minutes of the second half resulted in 23 total points scored by both teams with Souza and Dunning combining for three 3-pointers and the Tigers' Mitch Owens and Greg Lewis sinking a 3 each. UC Irvine went up 70-45 on a layup by Jaron Martin with 6:52 to play and the Anteaters never looked back.
Guilherme Guimaraes scored 11 points off the bench for the Tigers.