Justin Gordon scored 13, Lee Skinner added 12, and the Terriers (13-4, 4-0) outshot the Bulldogs 59.1 percent to 45.5 percent and outrebounded them 27-22.
Samford led 16-8 after a jumper by Michael Bradley, but Wofford tied it at 26 after Gordon made consecutive layups. Jamal Shabazz hit a 3-pointer and Samford led 32-31 at halftime.
Wofford pulled ahead 45-41 on a 3 and a layup by Cochran early in the second half, but Samford stayed close until Wofford ripped a 15-5 run in which Collins scored 10 to lead 67-55 with 1:10 left. Wofford outscored Samford 8-5 down the stretch.