The sophomore also had 22 in a loss to New Mexico on Jan. 10.
AJ West scored eight of Nevada's first 12 points, but Utah State pulled ahead 17-12 after a layup by Moore and led 29-19 at halftime.
West scored seven straight Wolf Pack points midway through the second half to pull Nevada within 50-45. The Aggies responded with 10 unanswered points, including 3s by Moore and Smith, then finished with a 7-2 run.
West led the Wolf Pack (6-11, 2-3) with 18 points and nine rebounds.