The Mustangs (18-4, 9-1 American Athletic Conference) remain a half-step behind Tulsa (16-5, 9-0) in conference.
Manuel was a near-perfect 9 of 10 from the field, adding four rebounds and four assists. Kennedy's rebounds were a season high and were a big part of SMU's 34-26 edge on the boards. The Mustangs controlled the paint, outscoring UCF 46-22, and 15-5 on second-chance baskets.
Adonys Henriquez led UCF (9-12, 2-8) with a career-high 22 points on six 3-pointers but was the only Knights player to reach double figures. The rest of the team shot 11 of 39. The Knights shot just 36 percent overall (19 of 53).