Yale goes to 15-6 overall and 4-0 in the Ivy League.
Cornell's Galal Cancer converted a pair of free throws with 12:50 left to give Cornell its final lead, 37-35. Duren answered with a 3-pointer and Yale rolled to the finish.
Amani Cotton pulled down 13 rebounds as the Bulldogs dominated the glass, 46-31. Yale shot 39.6 percent from the field (19 of 48) and 5 of 17 from distance. The Bulldogs knocked down 22 of 33 free throw attempts.
Shonn Miller scored 15 points to lead Cornell (10-10, 2-2), with Devin Cherry and Galal Cancer adding 14 and 12 points, respectably. The Big Red were 20 of 60 from the floor (33.3 percent) and 4 of 21 from beyond the arc.