Samford (12-14, 5-8 Southern) had five players in double figures, led by Darius Jones-Gibson with 13 points. Johnson finished with 12.
Tyler Hood made a corner 3-pointer to cut Samford's deficit to 66-64 and after an A.J. Merriweather basket, Johnson hit a 3 to make it 68-67. Later, Jones-Gibson made 1 of 2 free throws to tie the game at 68 with 39 seconds left. After an ETSU turnover, Johnson's game-winner capped a 7-0 run to close the game. Jalen Riley missed a 3-pointer at the buzzer.
Riley led ETSU (13-10, 6-7) with 20 points and Rashawn Rembert added 16.