Towson's A.J. Astroth hit a 3-pointer from the corner, and after a Drexel turnover, made a fast-break layup to pull Towson within 46-44 with 3:33 left. But Drexel scored the next five points for a 51-44 lead with 25 seconds left. After Towson scored the next five, Lee sealed it at the line.
Rodney Williams added 10 points for Drexel (10-14, 8-5 Colonial Athletic Association).
Lee had 15 points in the first half as Drexel built a 29-17 lead. The Dragons held Towson to 7-of-33 shooting (21.2 percent).
Towson went on a 13-4 run, with scoring from five different players, to cut its deficit to 33-30.