Greg Pryor added 11 points and five assists for Chattanooga (20-9, 13-3 Southern), which opened the second half with eight straight points to quickly erase a 30-22 halftime deficit. The Mocs took the lead for good at 40-38 during a 7-0 run and stretched the lead to 52-42 with 5:03 left.
A.J. Merriweather pulled ETSU (16-11, 8-8) within seven with 1:24 left, but Pryor made 8 of 10 free throws from there to seal the win.
Jalen Riley had 31 points for the second straight game for the Buccaneers. It was his fifth 30-point game this season. Merriweather added 12 points.
Chattanooga has remained one game behind first-place Wofford since starting the four-game winning streak on Feb. 12 with a 56-46 road win over the Terriers.