The game was Moss' 14th double-double of the season, tops in the MAC and 21st in the nation overall.
Shannon Evans also finished with a double-double for the Bulls (20-9, 11-6 Mid-American Conference), adding 16 points and 11 assists. Buffalo has now won five in a row, its longest winning streak of the season.
The Bulls shot 49.3 percent from the field, hit 10 3s, dished out 23 total assists, and the 93 points scored was their highest mark this year.
Buffalo, which is now tied atop the MAC East standings with Bowling Green, led 41-29 at the break. The Bulls opened the second on an 18-8 stretch to push their lead past 20.
Maurice Daly Ndour led Ohio (9-19, 4-13) with 25 points.