Tsalmpouris, a 7-foot-1 center from Katerini, Greece, was a late addition to the Cyclones roster last season.
Tsalmpouris was a project for former coach Fred Hoiberg. He played in just eight games as a freshman in 2014-15, averaging 1.4 points. The move was expected after Tsalmpouris returned to Greece this summer.
Tsalmpouris's departure frees up a scholarship for new coach Steve Prohm, who will lose four key contributors following next season.