Doyle made all six of his 3-point shots, including four in the final five minutes as Loyola (3-1) took its first lead since 17:30 in the first half. His final 3 came with 1:26 left and put the Ramblers up 64-60. Doyle had nine turnovers, eight of which came in the first half.
Loyola shot 59 percent from the field in the second half - including makes on eight of its last 10 shots - compared to just 34.6 percent for Toledo (2-1).
Nathan Boothe had 29 points, on 12-of-24 shooting, and grabbed 11 rebounds for the Rockets.
Toledo led by as many as 18 points.