Joshua Braun scored 20 points and added eight rebounds for Grand Canyon (4-0). The Antelopes shot 38 for 68 (55.9 percent) and outrebounded the Delta Devils 47-30. The Antelopes haven't started 4-0 since the 1996-97 season.
Latrell Love scored 16 points for Mississippi Valley State (0-4). Love was 4-for-8 shooting and 8 for 15 from the free-throw line. Issac Williams came off the bench to make five 3-pointers for 15 points.
Grand Canyon led 17-0 before Damian Young made a pair of free throws with 11:58 left before half.
The game was the first-ever meeting between the two schools.