Franko House scored 16 points, Bo Calhoun added 14 points, and Ryan Weber chipped in 13 for Ball State (4-2), which scored its most points of the season. Francis Kiapway made three 3-pointers and finished with nine points and a career-high four steals.
Jerome Campbell had 17 points on 6-of-14 shooting to lead Indiana-Kokomo.
An 11-0 run stretched Ball State's lead to 28-14 midway through the first half, and the Cardinals led 44-26 at halftime. House and Calhoun had 11 points apiece.
Kiapway made a 3-pointer to open the second half and spark a 22-7 surge, and the Cardinals led 66-33 with 12 minutes left. House scored five points and Calhoun hit a 3-pointer during the span.