Rathan-Mayes made two free throws for a 72-68 lead. Melvin Johnson hit a 3-pointer for VCU, his final points during his run of 16 straight, to cut the lead to one with 55 seconds left.
The Seminoles turned the ball over but Rathan-Mayes made a steal and Terance Mann dunked to make it 74-71. The Rams missed a 3-pointer and Rathan-Mayes sank two more free throws with six seconds left for the final score.
Florida State led 40-29 at halftime.