D'Vauntes Smith-Rivera added 12 points for Georgetown (5-3), which made 50 percent of its shots.
Georgetown held Brown to just two field goals in the first 10 minutes of the game and built a 46-16 lead by halftime. Brown was 7-of-30 shooting, including 1 of 12 from 3-point range, and missed all four free throw attempts before intermission. The Hoyas hit seven 3-pointers in the half.
Steven Spieth had 13 points and 12 rebounds for Brown (3-6). Tavon Blackmon added 11 points with five assists and JR Hobbie chipped in 10 points. The Bears were 16-of-57 shooting (28 percent), including 3 of 21 3-pointers.
Cedric Kuakumensah had a blocked shot with 16:33 remaining in the first half to set the Ivy League's career blocks record at 253.