Boone hit 9 of 14 shots from the field and 9 of 12 at the free throw line. Dorrian Williams added 14 points, seven boards, and five assists and Dequon Miller had 11 points for Missouri State (4-6), which has won three of four after starting the season 1-5.
The Bears shot 53.3 percent from the field while holding Oral Roberts to 35.9 percent.
Missouri State opened on an 18-2 run and led 45-22 at the half. A Jalen Bradley jumper for the Golden Eagles (8-4) trimmed their deficit 56-45 with 11 minutes left. But Missouri State answered with a 12-3 run to extend the lead back to 20 (68-48).
Obi Emegano scored 18 points for Oral Roberts.