Moore's layup with 4:25 left gave the Patriots a 66-56 lead with 4:25 to play. But the Lancers' Shaquille Johnson and Khris Lane hit back-to-back jumpers and Johnson threw down a dunk in less than a minute with 2:33 to play.
But Longwood's shots stopped falling and George Mason went 9-for-13 from the free-throw line down the stretch to put the game away.
Longwood managed to outshoot George Mason from the field by a margin of 51.8 percent to 39. However, the Lancers ended up shooting 7 for 17 from the free-throw line.
Shaquille Johnson led Longwood (3-9) with 23 points and 11 rebounds.