Western Carolina scored five straight points to tie the game at 52-all with 1:50 left. But Anthony Elechi put in a layup and Morehead State outscored Western Carolina 8-0. The Catamounts missed their last five shots.
The Eagles, coming in as the nation's 23rd-best scoring defense at 61.4 points per game, held the Catamounts to 30.6 percent shooting.
Justin Browning had 15 points and 10 rebounds, his first double-double for Western Carolina (4-7).
Morehead State scored the first six points of the second half for its biggest lead at 10 points. Western Carolina tied it with 9:42 left and lead changed hands six times after that.